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Looking back and moving forward: Questions and lessons 4 weeks out from Roche’s disappointing news
August 3, 2026
⏱️10min read | Roche’s decision to stop development of 2 HTT-lowering programmes is disappointing, but the story doesn’t end there. Years of research answered some…
July 2026: This Month in Huntington’s Disease Research
July 30, 2026
⏱️ 8 min read | July was a hard month for Huntington’s disease research, with Roche ending two HD programs. But the month also brought…
Putting it in print: a clinical trial trying to rein in runaway pruning
July 27, 2026
⏱️10 min read | Four years after announcing positive results in their trial of ANX005 (tanruprubart) for HD, Annexon has formally published the results. It’s…
Joining the Starting Lineup: MutLβ’s Role in DNA Repeat Expansions
July 23, 2026
⏱️8 min read | Scientists have known that MutLβ is linked to repeat expansion but not exactly how. A study reveals that the MutLβ protein…
Catching a Giant Protein: Five New Ways to Grab Huntingtin
July 20, 2026
⏱️8 min read | Scientists screened over a trillion tiny ring-shaped protein fragments to find ones that can grab onto the huntingtin. They captured huntingtin…