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Making babies: having a family, the HD way
For people at risk of Huntington’s disease, having a baby who might inherit HD can make decisions around planning a family extremely difficult. This article…
Steady progress from uniQure – promising data to end the year
With the holidays approaching, welcome news arrived on December 19th in a press release from uniQure. The latest data from the HD-GeneTRX studies of AMT-130,…
Putting it in print: GENERATION HD1 study results published
The outcomes of the GENERATION HD1 trial have just been published in a scientific journal, nearly three years after the study was halted. In March…
Regulating repetition: Gaining control of CAG repeats could slow progression of Huntington’s disease
“Somatic expansion” is a hot topic in Huntington’s disease research. Somatic expansion is a process in which CAG repeats lengthen in some cells during aging….
Beyond huntingtin lowering: out-of-the-box approaches for the treatment of HD
In recent years, HD research headlines have trended toward huntingtin lowering: experimental therapies that target the root genetic cause of HD. But there are also…