What’s happening?

Clinical trials for Huntington’s disease are happening worldwide right now. See HD Buzz clinical trial roundup from April 26, 2021. A lot is happening!

 

Are any clinical trials happening here in Australia?

 

  • The Roche Phase III GENERATION HD1 trial was discontinued in March 2021. The reason the trial was stopped was that the risks outweighed any benefits of the treatment. Within Australia, this international multisite trial was being run in Sydney and in two sites in Melbourne.
  • The Wave Life Sciences Phase 1b/2a trials PRECISION-HD1 and PRECISION-HD2 were also discontinued in March 2021. The reason this trial was stopped was that the treatment showed no benefit in patients taking the study drug compared to those taking the placebo. Within Australia, these trials were being conducted at sites in Perth, Brisbane, Sydney and Melbourne.
  • New HD trials are starting in Australia in late 2021 and early 2022. The HDNA will bring news of these trials as they develop.

I want to participate in a clinical trial. How do I volunteer?

 

  • Talk to your HD specialist about whether you may be eligible to participate in a clinical trial.
  • Keep in mind that clinical trials tend to have specific requirements for enrolment, and many people are ineligible. From time to time, check the HDNA website or the websites of HD state associations in case a trial comes up that may be right for you.
  • For more information on what to consider when participating in research, click here.

Where in Australia do clinical trials take place?

 

  • So far, clinical trials for HD in Australia have only been conducted at a handful of specialist clinics.
  • The HDNA works with HD specialists across Australia to facilitate the development of sites where clinical trials may potentially take place.