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When the Brain’s Clock Breaks: Sleep Disruption and Circadian Chaos in Huntington’s Disease

Sleep is more than a nightly recharge, it is fundamental to brain health. A landmark 12-year study tracking people with the gene for Huntington’s disease…

Pridopidine Hits a Roadblock: EMA Says No to Approval for Huntington’s Disease Treatment

We learned on July 25, 2025 that Prilenia’s application to the European Medicines Agency’s (EMA) for pridopidine was not accepted for marketing authorization. While this…

When the Brain’s Orchestra Falls Out of Tune: A New Map of Huntington’s Disease Progression

An international collaboration between world leaders in Huntington’s disease (HD) that spans both academia and pharmaceutical companies is giving us new insight into how HD…

Stopping the Genetic Snowball: How a simple genetic interruption slows Huntington’s disease

While the genetic change that causes Huntington’s disease (HD) leads to several problems for cells, researchers believe they could stem from one core issue: the…

Cracking the Case: How a Smartphone “Detective” is Helping Track Huntington’s Disease Progression

team of researchers from Roche and University College London (UCL) have developed a new clinical measure called the Huntington’s Disease Digital Motor Score (HDDMS). This…

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