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An Old Drug, New Tricks: Sertraline May Lighten the Load in HD by Targeting Protein Production
December 2, 2025
Depression and anxiety are common symptoms of Huntington’s disease (HD), and they can make everything harder. New research explores how sertraline, a widely-used antidepressant, affects…
November 2025: This Month in Huntington’s Disease Research
November 30, 2025
Welcome back to the HDBuzz monthly research roundup! November was a busy month, with new developments in everything from gene therapy and stem cells to…
Folding A Shirt With 12-Foot Arms: Understanding Protein Folding in Huntington’s Disease
November 25, 2025
Imagine a busy clothing factory. Proteins are like newly sewn shirts coming off the machines. They’re floppy, wrinkled, and can create a giant mess if…
SOM3355 Moves Toward Phase 3 as Both EMA and FDA Signal Support
November 21, 2025
SOM3355 is an investigational therapy aimed at managing multiple symptoms of Huntington’s disease (HD) and recently crossed two key regulatory milestones. In September, the European…
A Tiny Genetic Tweak Could Delay Symptoms and Activate Cellular Cleanup for Huntington’s Disease
November 18, 2025
Scientists often use genetics, the study of DNA, to understand the cellular changes that cause disease. By comparing people’s DNA with their symptoms, they can…