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2025 HDBuzz Prize: When Good Huntingtin Goes Missing: A Step Toward Designing Safe HD Treatments
A new study has shed light on the role of the regular huntingtin protein in the brain. For years, researchers have known that the faulty…
2025 HDBuzz Prize: On the Frontlines: Trusting the Hall Monitors of the Cell
Think about the last time you were stressed. What did you do to feel better? For many of us, it’s talking through our frustrations. Getting…
September 2025: This Month in Huntington’s Disease Research
This month brought landmark therapeutic news, advances in biomarkers, deeper insights into what drives Huntington’s disease (HD), and fresh perspectives on mental health in HD….
The First Domino Falls: AMT-130 Gene Therapy Slows Huntington’s in Landmark Trial
UniQure has announced positive top-line results from its Phase I/II trial of AMT-130, a one-time gene therapy being tested in people with Huntington’s disease (HD)….
2025 HDBuzz Prize: When the Repair Crew Breaks Down: How Expanded Huntingtin Disrupts DNA Repair
Every cell in our body is constantly fixing DNA damage that happens throughout our lifetime. Like a city sending out crews to mend roads and power lines,…