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Spark ignited: first HD patient dosed in new Roche gene therapy trial
Spark Therapeutics, recently integrated into Roche Pharmaceuticals, has been working on an HD gene therapy. It’s delivered via a one-time brain surgery and is designed…
The latest volume of HD genetics research reveals new gems but also mysteries
The latest instalment in a series of big studies to understand the genetics of Huntington disease (HD) just hit the shelves. These studies have focused…
When a Short Fuse Becomes a Storm: Understanding Irritability in Huntington’s Disease
We all have days when we feel irritable, like when you’re stuck in traffic, or someone cuts in line at the grocery store. But for…
Inside the Brain’s Theme Park: How Huntington’s Disease Disrupts the Emotion Coaster
Welcome to Brainland, the bustling, 24/7 theme park in your head. There’s Memory Maze, Logic Log Flume, and of course, the Emotion Coaster, where your…
One Disease, Many Paths: How Brain Wiring Shapes Huntington’s Symptoms
Huntington’s disease (HD) is caused by a single genetic mutation, yet people with HD can experience vastly different symptoms – from movement issues to emotional…